The following is a list of guests featured on The Tonight Show.
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|---|---|---|---|---|---|---|---|---|---|---|
| Date | Guest(s) | Musical guests | ||||||||
| June 1, 2009 | Will Ferrell | Pearl Jam | ||||||||
| June 2, 2009 | Tom Hanks | Green Day | ||||||||
| June 3, 2009 | Julia Louis-Dreyfus, Bradley Cooper | Sheryl Crow | ||||||||
| June 4, 2009 | Gwyneth Paltrow | John Mayer Trio | ||||||||
| June 5, 2009 | Ryan Seacrest | Chickenfoot | ||||||||
| June 8, 2009 | David Duchovny | Anna Friel | ||||||||
| June 9, 2009 | Bonnie Raitt | |||||||||
| June 10, 2009 | Dane Cook | Rancid | ||||||||
| June 11, 2009 | Jim Gaffigan | Neko Case | ||||||||
| June 12, 2009 | Jamie Foxx, Kevin Nealon | Jamie Foxx | ||||||||
November 24, 2010 Ready Steady cook chefs the full monty